Overview

  • Product nameAnti-POLR2C antibody
    See all POLR2C primary antibodies
  • Description
    Chicken polyclonal to POLR2C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Full length protein (Human).

  • Positive control
    • E coli-derived POLR2C fusion protein.
  • General notesDuring shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.

Properties

Applications

Our Abpromise guarantee covers the use of ab14252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 33 kDa.

Target

  • FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.
  • Sequence similaritiesBelongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA directed RNA polymerase II 33 kDa polypeptide antibody
    • DNA directed RNA polymerase II subunit C antibody
    • DNA directed RNA polymerase II subunit RPB3 antibody
    • DNA-directed RNA polymerase II 33 kDa polypeptide antibody
    • DNA-directed RNA polymerase II subunit C antibody
    • DNA-directed RNA polymerase II subunit RPB3 antibody
    • hRPB33 antibody
    • hsRPB3 antibody
    • POLR 2C antibody
    • POLR2 C antibody
    • Polr2c antibody
    • Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa antibody
    • polymerase RNA II DNA directed polypeptide C 33kDa antibody
    • RNA polymerase II polypeptide C antibody
    • RNA polymerase II subunit 3 antibody
    • RNA polymerase II subunit B3 antibody
    • RPB 3 antibody
    • RPB3 antibody
    • RPB3_HUMAN antibody
    • RPB31 antibody
    • RPB33 antibody
    see all

Anti-POLR2C antibody images



  • Predicted band size : 33 kDa


    Western blot detection of E coli-derived POLR2C fusion protein. IgY dilutions: 1:2000, goat anti-IgY Fc-HRP: 1:1000, colorimetric method for signal development.

References for Anti-POLR2C antibody (ab14252)

This product has been referenced in:
  • Ujvári A  et al. The Functions of TFIIF during Initiation and Transcript Elongation Are Differentially Affected by Phosphorylation by Casein Kinase 2. J Biol Chem 286:23160-7 (2011). WB ; Human . Read more (PubMed: 21566144) »
  • Brem R  et al. Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions. Nucleic Acids Res 37:1951-61 (2009). WB ; Human . Read more (PubMed: 19208641) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"