Overview

  • Product nameAnti-POLR2G antibody
    See all POLR2G primary antibodies
  • Description
    Rabbit polyclonal to POLR2G
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Zebrafish
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 1 and 142 of POLR2G (NP_002687).

  • Positive control
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates IHC-P: CL1-5 xenograft

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab96031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 19 kDa.
IHC-P 1/100 - 1/500.

Target

  • FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.
  • Sequence similaritiesBelongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA directed RNA polymerase II 19 kDa polypeptide antibody
    • DNA directed RNA polymerase II subunit G antibody
    • DNA directed RNA polymerase II subunit RPB7 antibody
    • DNA-directed RNA polymerase II subunit G antibody
    • DNA-directed RNA polymerase II subunit RPB7 antibody
    • hRPB19 antibody
    • hsRPB7 antibody
    • MGC138367 antibody
    • MGC138369 antibody
    • POLR2G antibody
    • polymerase (RNA) II (DNA directed) polypeptide G antibody
    • RNA polymerase II 19 kDa subunit antibody
    • RNA polymerase II subunit B7 antibody
    • RPB19 antibody
    • RPB7 antibody
    • RPB7_HUMAN antibody
    see all

Anti-POLR2G antibody images

  • Anti-POLR2G antibody (ab96031) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 19 kDa
  • Immunohistochemical analysis of POLR2G in paraffin embedded CL1-5 xenograft, using ab96031 at a 1/500 dilution.

References for Anti-POLR2G antibody (ab96031)

ab96031 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"