1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
FunctionCapable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Tissue specificityWidely expressed with highest expression in liver, lung, placenta, testis and heart.
Sequence similaritiesBelongs to the paraoxonase family.
Post-translational modificationsThe signal sequence is not cleaved.