Overview

  • Product nameAnti-PON2 antibody
    See all PON2 primary antibodies
  • Description
    Goat polyclonal to PON2
  • SpecificityThis antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Dog, Pig
  • Immunogen

    Synthetic peptide:

    EKPRARELRIS

    by a Cysteine residue linker, corresponding to internal sequence amino acids 93-103 of Human PON2 (NP_000296.2; NP_001018171.1)

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa).

Target

  • FunctionCapable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
  • Tissue specificityWidely expressed with highest expression in liver, lung, placenta, testis and heart.
  • Sequence similaritiesBelongs to the paraoxonase family.
  • Post-translational
    modifications
    The signal sequence is not cleaved.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • A esterase 2 antibody
    • A-esterase 2 antibody
    • Aromatic esterase 2 antibody
    • Paraoxonase 2 antibody
    • Paraoxonase nirs antibody
    • PON 2 antibody
    • PON2 antibody
    • PON2_HUMAN antibody
    • Serum aryldialkylphosphatase 2 antibody
    • Serum paraoxonase/arylesterase 2 antibody
    see all

Anti-PON2 antibody images

  • Anti-PON2 antibody (ab99550) at 1 µg/ml (incubation time 1 hour) + HepG2 cell lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

References for Anti-PON2 antibody (ab99550)

ab99550 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"