Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab106797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 0.6 µg/ml. Predicted molecular weight: 40 kDa.

Target

  • Function
    May play a role in determining or maintaining the identities of a small subset of visual system neurons.
  • Tissue specificity
    Brain. Seems to be specific to the retina.
  • Involvement in disease
    Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15) [MIM:602459]. DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • Sequence similarities
    Belongs to the POU transcription factor family. Class-4 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Brain specific homeobox/POU domain protein 3C antibody
    • Brain-3C antibody
    • Brain-specific homeobox/POU domain protein 3C antibody
    • BRN 3C antibody
    • Brn-3C antibody
    • BRN3C antibody
    • class 4 antibody
    • DFNA 15 antibody
    • DFNA15 antibody
    • MGC138412 antibody
    • PO4F3_HUMAN antibody
    • POU class 4 homeobox 3 antibody
    • POU domain antibody
    • POU domain class 4 transcription factor 3 antibody
    • POU4F3 antibody
    • transcription factor 3 antibody
    see all

Images

  • Anti-POU4F3 antibody (ab106797) at 0.2 µg/ml + Human Heart lysate at 35 µg

    Predicted band size : 40 kDa

References

ab106797 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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