The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/5500 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
RelevancePP14C is an inhibitor of PPP1CA. It has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. It is found in breast carcinoma.