Overview

  • Product nameAnti-PPFIA4 antibody
    See all PPFIA4 primary antibodies
  • Description
    Mouse monoclonal to PPFIA4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: RQVMEREFNN LLALGTDRKL DDGDDKVFRR APSWRKRFRP REHHGRGGML SASAETLPAG FRVSTLGTLQ PPPAPPKKIM PEAHSHYLYG HMLSAF, corresponding to amino acids 604-700 of Human PPFIA4

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
    • Tissue specificityExpressed only in the heart, brain, and skeletal muscle.
    • Sequence similaritiesBelongs to the liprin family. Liprin-alpha subfamily.
      Contains 3 SAM (sterile alpha motif) domains.
    • DomainThe N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
    • Cellular localizationCytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA0897 antibody
      • LIPA4_HUMAN antibody
      • Liprin alpha 4 antibody
      • Liprin-alpha-4 antibody
      • PPFIA 4 antibody
      • PPFIA4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 4 antibody
      • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4 antibody
      • PTPRF interacting protein alpha 4 antibody
      • PTPRF-interacting protein alpha-4 antibody
      see all

    Anti-PPFIA4 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56339 PPFIA4 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-PPFIA4 antibody (ab56339)

    This product has been referenced in:
    • Kiok K  et al. Liprin-a4 Is Required for Nickel Induced Receptor Protein Tyrosine Phosphatase-Leukocyte Antigen Related Receptor F (RPTP-LAR) Activity. PLoS One 6:e22764 (2011). WB ; Human . Read more (PubMed: 21829649) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab56339.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"