Overview

  • Product name
  • Description
    Rabbit polyclonal to PPHLN1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human PPHLN1 (internal sequence). The exact sequence is proprietary. 16 amino acids. NP_057572.5.
    Database link: Q8NEY8

  • Positive control
    • Human brain cortex and colon tissues; mouse colon tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab189998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.
  • Tissue specificity
    Ubiquitous.
  • Post-translational
    modifications
    Substrate of transglutaminase (in vitro).
  • Cellular localization
    Nucleus. Cytoplasm. In undifferentiated keratinocytes expressed in speckle-type nuclear granules and at the nuclear membrane, but in the differentiated keratinocytes colocalized with periplakin at the cell periphery and at cell-cell junctions.
  • Information by UniProt
  • Database links
  • Alternative names
    • Gastric cancer antigen Ga50 antibody
    • Periphilin 1 antibody
    • Periphilin-1 antibody
    • PPHLN_HUMAN antibody
    • PPHLN1 antibody
    see all

Images

  • All lanes : Anti-PPHLN1 antibody (ab189998) at 1 µg/ml

    Lane 1 : mouse colon tissue lysate
    Lane 2 : mouse colon tissue lysate with blocking peptide

    Predicted band size: 53 kDa

  • Immunofluorescent analysis of Human colon tissue labeling PPHLN1 with ab189998 at 5 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cortex tissue labeling PPHLN1 with ab189998 at 10 µg/ml.

References

ab189998 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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