Overview

  • Product name
    Anti-PPIP5K2 antibody - N-terminal
    See all PPIP5K2 primary antibodies
  • Description
    Rabbit polyclonal to PPIP5K2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within N terminal amino acids 5-341 of Human PPIP5K2 (Uniprot ID; O43314).

  • Positive control
    • Raji and K562 whole cell lysates; Human PC13 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 140 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer.
  • Sequence similarities
    Belongs to the histidine acid phosphatase family. VIP1 subfamily.
  • Cellular localization
    Cytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Diphosphoinositol pentakisphosphate kinase 2 antibody
    • HISPPD1 antibody
    • Histidine acid phosphatase domain containing 1 antibody
    • Histidine acid phosphatase domain containing protein 1 antibody
    • Histidine acid phosphatase domain-containing protein 1 antibody
    • hsVIP2 antibody
    • Inositol heptaphosphate kinase 2 antibody
    • Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 antibody
    • InsP6 and PP IP5 kinase 2 antibody
    • InsP6 and PP-IP5 kinase 2 antibody
    • IP7K2 antibody
    • PP IP5 kinase 2 antibody
    • Ppip5k2 antibody
    • VIP1 homolog 2 antibody
    • VIP2 antibody
    • VIP2_HUMAN antibody
    see all

Images

  • All lanes : Anti-PPIP5K2 antibody - N-terminal (ab154046) at 1/3000 dilution

    Lane 1 : Raji whole cell lysate
    Lane 2 : K562 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 140 kDa



    5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human PC13 xenograft tissue, labeling PPIP5K2 with ab154046 at 1/500 dilution.

References

This product has been referenced in:
  • Gu C  et al. Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels. PLoS One 11:e0165286 (2016). WB ; Human . Read more (PubMed: 27788189) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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