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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.09% Sodium Azide
Concentration information loading...
Purity Ammonium Sulphate Precipitation
Purification notes This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
Function Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.
Sequence similarities Belongs to the PP2C family.
Cellular localization Nucleus.
Information by UniProt
Protein phosphatase 2C isoform alpha antibody
EC 18.104.22.168 antibody
Anti-PPM1A antibody images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PPM1A antibody (ab60237)
Ab60237 (1/50-1/100) staining human PPM1A in human breast carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
BC = breast carcinoma
References for Anti-PPM1A antibody (ab60237)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"