Overview

  • Product nameAnti-PPM1E antibody
    See all PPM1E primary antibodies
  • Description
    Rabbit polyclonal to PPM1E
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen, corresponding to internal sequence amino acids 491-574 of Human PPM1E.

  • Positive control
    • Human rectum tissue; Human Liver and Tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab121598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionProtein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42.
  • Sequence similaritiesBelongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • Cellular localizationNucleus. Cytoplasm. A truncated form, major form, with the C-terminal part missing, is mostly found in the cytoplasm and a little in the nucleus. The full length, minor form, is found in the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ca(2+)/calmodulin-dependent protein kinase phosphatase N antibody
    • CaMKN antibody
    • CaMKP-N antibody
    • CaMKP-nucleus antibody
    • KIAA1072 antibody
    • Nuclear calmodulin dependent protein kinase phosphatase antibody
    • Partner of PIX 1 antibody
    • Partner of PIX-alpha antibody
    • Partner of PIXA antibody
    • POPX1 antibody
    • PP2CH antibody
    • Ppm1e antibody
    • PPM1E_HUMAN antibody
    • Protein phosphatase 1E antibody
    • Protein phosphatase Mg2+/Mn2+ dependent 1E antibody
    see all

Anti-PPM1E antibody images

  • ab121598 at 1/200 dilution staining PPM1E in Paraffin-embedded Human Rectum tissue by Immunohistochemistry.
    Note: strong cytoplasmic positivity in glandular cells.

References for Anti-PPM1E antibody (ab121598)

ab121598 has not yet been referenced specifically in any publications.

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