Overview

  • Product name
    Anti-PPM1L antibody
  • Description
    Rabbit polyclonal to PPM1L
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 215-244 of Human PPM1L (NP_640338.2).

  • Positive control
    • Mouse heart tissue lysate Human lung tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab107642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
  • Tissue specificity
    Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas.
  • Sequence similarities
    Belongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 3.1.3.16 antibody
    • in phosphatase 1 (formerly 2C) like antibody
    • MGC132545 antibody
    • MGC132547 antibody
    • OTTHUMP00000213920 antibody
    • OTTHUMP00000213921 antibody
    • PP2C epsilon antibody
    • PP2C-epsilon antibody
    • PP2CE antibody
    • PPM1 like antibody
    • PPM1-LIKE antibody
    • PPM1L antibody
    • PPM1L_HUMAN antibody
    • Protein phosphatase 1 (formerly 2C)-like antibody
    • Protein phosphatase 1 like antibody
    • Protein phosphatase 1-like antibody
    • Protein phosphatase 1L antibody
    • Protein phosphatase 2C epsilon isoform antibody
    • Protein phosphatase 2C isoform epsilon antibody
    • Protein phosphatase, Mg2+/Mn2+ dependent, 1L antibody
    see all

Images

  • Anti-PPM1L antibody (ab107642) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size : 41 kDa
  • ab107642, at 1/50, staining PPM1L in formalin fixed and paraffin embedded Human lung tissue by Immunohistochemistry. Developed using peroxidase conjugation of the secondary antibody and DAB staining.

References

ab107642 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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