Overview

  • Product name
  • Description
    Rabbit polyclonal to PPP1R12C
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: DIARYLLSHG ANIAAVNSDG DLPLDLAESD AMEGLLKAEI ARRGVDVEAA KRAEEELLLH DTRCWLNGGA MPEARHPRTG ASALHV, corresponding to amino acids 148-233 of Human PPP1R12C (Q9BZL4).

  • Positive control
    • U-251 MG, Human Liver and Human tonsil lysates, Human liver tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab126362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Regulates myosin phosphatase activity.
  • Tissue specificity
    Ubiquitously expressed. Highly expressed in heart.
  • Sequence similarities
    Contains 4 ANK repeats.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Along actomyosin filaments and stress fibers.
  • Information by UniProt
  • Database links
  • Alternative names
    • LENG 3 antibody
    • LENG3 antibody
    • leukocyte receptor cluster (LRC) encoded novel gene 3 antibody
    • leukocyte receptor cluster (LRC) member 3 antibody
    • MBS 85 antibody
    • MBS85 antibody
    • Myosin binding subunit 85 antibody
    • p84 antibody
    • p85 antibody
    • PP12C_HUMAN antibody
    • Ppp1r12c antibody
    • protein phosphatase 1 regulatory (inhibitor) subunit 12C antibody
    • protein phosphatase 1 myosin binding subunit of 85 kDa antibody
    • protein phosphatase 1 myosin binding subunit p85 antibody
    • Protein phosphatase 1 myosin-binding subunit of 85 kDa antibody
    • Protein phosphatase 1 myosin-binding subunit p85 antibody
    • Protein phosphatase 1 regulatory subunit 12C antibody
    see all

Images

  • ab126362, at a dilution of 1/1000, staining PPP1R12C in paraffin-embedded Human liver tissue by Immunohistochemistry.

References

ab126362 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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