Overview

  • Product name
  • Description
    Rabbit polyclonal to PPP1R15B
  • Tested applications
    Suitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from the C terminal domain of human PPP1R15B.

Properties

Applications

Our Abpromise guarantee covers the use of ab76785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/50 - 1/200.
WB 1/100 - 1/1000. Predicted molecular weight: 79 kDa.

Target

  • Relevance
    PPP1R15B belongs to the PPP1R15 family. It maintains low levels of EIF2S1 phosphorylation in un-stressed cells by promoting its dephosphorylation by PP1. The phosphatase activity of the PPP1R15B-PP1 complex toward EIF2S1 is specifically inhibited by Salubrinal, a drug that protects cells from endoplasmic reticulum stress.
  • Database links
  • Alternative names
    • CREP antibody
    • FLJ14744 antibody
    • PPP1R15B antibody
    • Protein phosphatase 1, regulatory (inhibitor) subunit 15B antibody
    • Protein phosphatase 1, regulatory subunit 15B antibody
    see all

References

ab76785 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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