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Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium Azide
Concentration information loading...
Purity Immunogen affinity purified
Purification notes This antibody is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 126 kDa.
Function Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
Tissue specificity Skeletal muscle and heart.
Involvement in disease Diabetes mellitus, non-insulin-dependent
Sequence similarities Contains 1 CBM21 (carbohydrate binding type-21) domain.
Domain The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
Post-translational modifications Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
Cellular localization Membrane.
Information by UniProt
Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody
Glycogen associated regulatory subunit of protein phosphatase 1 antibody
Anti-PPP1R3A antibody images
References for Anti-PPP1R3A antibody (ab107367)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"