Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab18136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.
ICC 1/500 - 1/1000.
IHC-P Use at an assay dependent concentration. PubMed: 23887057

Target

  • Function
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • Tissue specificity
    Expressed in all tissues examined.
  • Sequence similarities
    Belongs to the phosphatase 2A regulatory subunit B family.
    Contains 7 WD repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2ABA_HUMAN antibody
    • Alpha isoform of regulatory subunit B55 protein phosphatase 2 antibody
    • B55A antibody
    • B55ALPHA antibody
    • calcineurin antibody
    • PP2A subunit B B alpha isoform antibody
    • PP2A subunit B B55 alpha isoform antibody
    • PP2A subunit B isoform alpha antibody
    • PP2A subunit B isoform B55-alpha antibody
    • PP2A subunit B isoform PR55-alpha antibody
    • PP2A subunit B isoform R2-alpha antibody
    • PP2A subunit B PR55 alpha isoform antibody
    • PP2A subunit B R2 alpha isoform antibody
    • PPP2R2A antibody
    • PR52A antibody
    • PR55A antibody
    • Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) alpha isoform antibody
    • Protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform antibody
    • Protein phosphatase 2 regulatory subunit B alpha antibody
    • Protein phosphatase 2 regulatory subunit B alpha isoform antibody
    • Protein phosphatase 2 regulatory subunit Balpha antibody
    • Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform antibody
    • Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform antibody
    • Testicular tissue protein Li 156 antibody
    see all

References

This product has been referenced in:
  • Cristóbal I  et al. PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol Cancer Ther 13:938-47 (2014). Read more (PubMed: 24448818) »
  • Shen R  et al. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models. Cancer Lett 339:135-43 (2013). IHC-P ; Mouse . Read more (PubMed: 23887057) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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