For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to PPP2R2A
Mouse, Rat, Cow, Human
conjugated to KLH, corresponding to N terminal amino acids 14-27 of PPP2R2A
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 56 kDa.
1/500 - 1/1000.
Use at an assay dependent concentration. PubMed: 23887057
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Expressed in all tissues examined.
Belongs to the phosphatase 2A regulatory subunit B family.
Contains 7 WD repeats.
Information by UniProt
Alpha isoform of regulatory subunit B55 protein phosphatase 2 antibody
References for Anti-PPP2R2A antibody (ab18136)
This product has been referenced in:
et al. PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol Cancer Ther 13:938-47 (2014).
Read more (PubMed: 24448818) »
et al. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models. Cancer Lett 339:135-43 (2013).
Read more (PubMed: 23887057) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"