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Goat polyclonal to PPP2R5D
Predicted to work with:
Synthetic peptide: KRAEEFLTASQEAL, corresponding to C terminal amino acids 589-602 of Human PPP2R5D.
Principal Names – PPP2R5D; protein phosphatase 2, regulatory subunit B (B56), delta isoform
Official Gene Symbol - PPP2R5D
GenBank Accession Number – NP_006236
LocusLink ID - 5528 (human); 21770 (mouse)
Gene Ontology terms - nucleus; neurogenesis; protein phosphatase type 2A regulator
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
Concentration information loading...
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. Can be blocked with
Human PPP2R5D peptide (ab22817).
Approx 70kDa and 60kDa bands seen in 293 lysate (Predicted MW of 68kDa and 62kDa according to NP_006236 and AAH01175, respectively).
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
Belongs to the phosphatase 2A regulatory subunit B56 family.
Cytoplasm. Nucleus. Nuclear in interphase, nuclear during mitosis.
Information by UniProt
References for Anti-PPP2R5D antibody (ab1361)
This product has been referenced in:
et al. Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity. J Neurosci 30:8830-40 (2010).
Read more (PubMed: 20592205) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"