Overview

  • Product nameAnti-PPP2R5D antibody
    See all PPP2R5D primary antibodies
  • Description
    Goat polyclonal to PPP2R5D
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide: KRAEEFLTASQEAL, corresponding to C terminal amino acids 589-602 of Human PPP2R5D.

  • Positive control
    • WB: 293 cell lysate.
  • General notesPrincipal Names – PPP2R5D; protein phosphatase 2, regulatory subunit B (B56), delta isoform Official Gene Symbol - PPP2R5D GenBank Accession Number – NP_006236 LocusLink ID - 5528 (human); 21770 (mouse) Gene Ontology terms - nucleus; neurogenesis; protein phosphatase type 2A regulator

Properties

Applications

Our Abpromise guarantee covers the use of ab1361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Can be blocked with Human PPP2R5D peptide (ab22817).

 Approx 70kDa and 60kDa bands seen in 293 lysate (Predicted MW of 68kDa and 62kDa according to NP_006236 and AAH01175, respectively).

Target

  • FunctionThe B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • Tissue specificityIsoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
  • Sequence similaritiesBelongs to the phosphatase 2A regulatory subunit B56 family.
  • Cellular localizationCytoplasm. Nucleus. Nuclear in interphase, nuclear during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2A5D_HUMAN antibody
    • B'delta antibody
    • B56D antibody
    • Delta isoform of regulatory subunit B56, protein phosphatase 2A antibody
    • MGC2134 antibody
    • MGC8949 antibody
    • OTTHUMP00000039821 antibody
    • PP2A B subunit B' delta isoform antibody
    • PP2A B subunit B56 delta isoform antibody
    • PP2A B subunit isoform B''-delta antibody
    • PP2A B subunit isoform B56-delta antibody
    • PP2A B subunit isoform PR61-delta antibody
    • PP2A B subunit isoform R5-delta antibody
    • PP2A B subunit PR61 delta isoform antibody
    • PP2A B subunit R5 delta isoform antibody
    • PPP2R5D antibody
    • Protein phosphatase 2 regulatory subunit B (B56) delta isoform antibody
    • Protein phosphatase 2 regulatory subunit B delta isoform antibody
    • Protein phosphatase 2 regulatory subunit B' delta antibody
    • Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform antibody
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform antibody
    • TEG-271 antibody
    • Tex271 antibody
    see all

References for Anti-PPP2R5D antibody (ab1361)

This product has been referenced in:
  • Kapfhamer D  et al. Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity. J Neurosci 30:8830-40 (2010). WB ; Mouse . Read more (PubMed: 20592205) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"