Overview

  • Product nameAnti-PR3 antibody
    See all PR3 primary antibodies
  • Description
    Rabbit polyclonal to PR3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length Human PR3 (AAH96184.1, amino acids 1-256).

  • Positive control
    • Mouse brain tissue lysate, PR3 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103632 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 28 kDa.

Target

  • FunctionPolymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
  • Sequence similaritiesBelongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACPA antibody
    • AGP 7 antibody
    • AGP7 antibody
    • AGP7 serine proteinase antibody
    • Azurophil Granule Protein 7 antibody
    • C ANCA antibody
    • C ANCA antigen antibody
    • C-ANCA antigen antibody
    • CANCA antibody
    • EC 3.4.21.76 antibody
    • Leukocyte proteinase 3 antibody
    • MBN antibody
    • MBT antibody
    • MBT WEGENER AUTOANTIGEN antibody
    • Myeloblastin antibody
    • Neutrophil proteinase 4 antibody
    • NP 4 antibody
    • NP-4 antibody
    • NP4 antibody
    • P29 antibody
    • PR 3 antibody
    • PR-3 antibody
    • PR3 antibody
    • Proteinase 3 antibody
    • Proteinase3 antibody
    • PRTN 3 antibody
    • Prtn3 antibody
    • PRTN3_HUMAN antibody
    • Serine proteinase neutrophil Wegener granulomatosis autoantigen antibody
    • Serine proteinase, neutrophil antibody
    • Wegener autoantigen antibody
    • Wegener granulomatosis autoantigen antibody
    see all

Anti-PR3 antibody images

  • Anti-PR3 antibody (ab103632) at 5 µg/ml + Mouse brain tissue lysate at 50 µg

    Predicted band size : 28 kDa
  • All lanes : Anti-PR3 antibody (ab103632) at 5 µg/ml

    Lane 1 : PR3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 28 kDa

References for Anti-PR3 antibody (ab103632)

This product has been referenced in:
  • Sørensen OE  et al. Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses. J Clin Invest 124:4539-48 (2014). WB ; Human . Read more (PubMed: 25244098) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"