General notesab94310 is a 293T cell transfected lysate in which Human PR3 has been transiently over-expressed using a pCMV-PR3 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Similarity: Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain.