Overview

  • Product name
  • Description
    Rabbit polyclonal to PRAM1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 161-243 of Human PRAM1.

  • Positive control
    • Human bone marrow tissue; RT-4, U-251 MG, Human liver and Human tonsil lysates.
  • General notes
    The antibody solution should be gently mixed before use.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500. Predicted molecular weight: 79 kDa.

Target

  • Function
    May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P.
  • Tissue specificity
    Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung.
  • Sequence similarities
    Contains 1 SH3 domain.
  • Domain
    The SH3 domain binds to PtdIns(4)P.
  • Post-translational
    modifications
    May be phosphorylated on tyrosines.
  • Information by UniProt
  • Database links
  • Alternative names
    • PML RAR antibody
    • PML RARA regulated adaptor molecule 1 antibody
    • PML RARA target gene encoding an Adaptor Molecule 1 antibody
    • PML-RARA-regulated adapter molecule 1 antibody
    • PRAM 1 antibody
    • PRAM antibody
    • PRAM-1 antibody
    • PRAM_HUMAN antibody
    • PRAM1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human bone marrow tissue labeling PRAM1 with ab151092 at 1/500 dilution.
  • All lanes : Anti-PRAM1 antibody (ab151092) at 1/250 dilution

    Lane 1 : RT-4 lysate
    Lane 2 : U-251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Predicted band size: 79 kDa

References

ab151092 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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