Overview

  • Product nameAnti-PRAME antibody
    See all PRAME primary antibodies
  • Description
    Rabbit polyclonal to PRAME
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Horse, Cow, Cat, Pig
  • Immunogen

    Synthetic peptide within residues: ERRRLWGSIQ SRYISMSVWT SPRRLVELAG QSLLKDEALA IAALELLPRE, corresponding to N terminal amino acids 2-51 of Human PRAME (NP_006106)

  • Positive control
    • Human fetal brain lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionFunctions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
  • Tissue specificityExpressed in testis. Detected in samples of kidney, brain and skin.
  • Sequence similaritiesBelongs to the PRAME family.
    Contains 4 LRR (leucine-rich) repeats.
  • Cellular localizationNucleus. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4930534P07Rik antibody
    • Cancer/testis antigen 130 antibody
    • CT130 antibody
    • MAPE antibody
    • Melanoma antigen preferentially expressed in tumors antibody
    • OIP 4 antibody
    • OIP-4 antibody
    • OIP4 antibody
    • OPA interacting protein 4 antibody
    • Opa interacting protein OIP4 antibody
    • OPA-interacting protein 4 antibody
    • PRAME antibody
    • PRAME_HUMAN antibody
    • Preferentially expressed antigen in melanoma antibody
    • Preferentially expressed antigen of melanoma antibody
    • RP23-250F8.3 antibody
    see all

Anti-PRAME antibody images

  • Anti-PRAME antibody (ab90052) at 1 µg/ml + Human fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa
    Observed band size : 58 kDa

References for Anti-PRAME antibody (ab90052)

ab90052 has not yet been referenced specifically in any publications.

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