Overview

  • Product nameAnti-PRAX-1 antibody
    See all PRAX-1 primary antibodies
  • Description
    Rabbit polyclonal to PRAX-1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 12-120 of Human PRAX-1.

  • Positive control
    • Human kidney tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab121838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificityPredominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus.
  • Sequence similaritiesBelongs to the RIMBP family.
    Contains 3 fibronectin type-III domains.
    Contains 3 SH3 domains.
  • DomainThe SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2.
  • Cellular localizationCytoplasm. Mitochondrion. Preferentially expressed in the mitochondria in the presence of BZRP.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bzrap1 antibody
    • D230016K05 antibody
    • mKIAA0612 antibody
    • PBR-IP antibody
    • Peripheral benzodiazepine receptor-interacting protein antibody
    • Peripheral-type benzodiazepine receptor-associated protein 1 antibody
    • PRAX 1 antibody
    • PRAX-1 antibody
    • RBP1 antibody
    • RIM binding protein 1 antibody
    • RIM-BP1 antibody
    • RIMB1_HUMAN antibody
    • RIMBP1 antibody
    • RIMS-binding protein 1 antibody
    • RP23-449P23.4 antibody
    see all

Anti-PRAX-1 antibody images

  • ab121838 at 1/250 dilution staining PRAX-1 in Paraffin-embedded Human kidney tissue by Immunohistochemistry. Note: strong granular cytoplasmic positivity tubular cells.

References for Anti-PRAX-1 antibody (ab121838)

ab121838 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"