Overview

  • Product name
  • Description
    Goat polyclonal to PRDM9
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide corresponding to Rat PRDM9 aa 440-451 (internal sequence) (Cysteine residue). NP_001102373.2.
    Sequence:

    QEHFDSQNKNDK


    Database link: P0C6Y7

  • Positive control
    • Rat spleen lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab178531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 - 3 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 95 kDa).

Target

  • Function
    Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase.
  • Sequence similarities
    Contains 14 C2H2-type zinc fingers.
    Contains 1 KRAB-related domain.
    Contains 1 SET domain.
  • Cellular localization
    Nucleus. Chromosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 2.1.1.43 antibody
    • Histone lysine N methyltransferase PRDM9 antibody
    • Histone-lysine N-methyltransferase PRDM9 antibody
    • MEISETZ antibody
    • PFM6 antibody
    • PR domain containing 9 antibody
    • PR domain containing protein 9 antibody
    • PR domain zinc finger protein 9 antibody
    • PR domain-containing protein 9 antibody
    • PRDM 9 antibody
    • PRDM9 antibody
    • PRDM9_HUMAN antibody
    see all

Images

  • Anti-PRDM9 antibody (ab178531) at 2 µg/ml + Rat Ovary Lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 95 kDa

    Primary incubation 1 hour

  • Anti-PRDM9 antibody (ab178531) at 0.5 µg/ml + Rat spleen lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 95 kDa
    Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.

References

ab178531 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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