Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody (ab84549)

Overview

  • Product name
    Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody
    See all pre-mRNA cleavage factor I (59 kDa subunit) primary antibodies
  • Description
    Rabbit polyclonal to pre-mRNA cleavage factor I (59 kDa subunit)
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Dog, Chimpanzee, Rhesus monkey, Orangutan, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region within the amino acids 175-225 of human pre-mRNA cleavage factor I (59 kDa subunit) (NP_079087.2).

  • Positive control
    • Human breast carcinoma, ovarian carcinoma.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab84549 was affinity purified using an epitope specific to pre-mRNA cleavage factor I (59 kDa subunit) immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3' processing. Binds to cleavage and polyadenylation RNA substrates.
    • Sequence similarities
      Belongs to the RRM CPSF6/7 family.
      Contains 1 RRM (RNA recognition motif) domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CFIm59 antibody
      • Cleavage and polyadenylation specificity factor 59 kDa subunit antibody
      • Cleavage and polyadenylation specificity factor 7 antibody
      • Cleavage and polyadenylation specificity factor subunit 7 antibody
      • CPSF 59 kDa subunit antibody
      • Cpsf7 antibody
      • CPSF7_HUMAN antibody
      • FLJ12529 pre mRNA cleavage factor I 59 kDa subunit antibody
      • FLJ39024 antibody
      • MGC9315 antibody
      • Pre mRNA cleavage factor Im 59 kDa subunit antibody
      • Pre-mRNA cleavage factor Im 59 kDa subunit antibody
      see all

    Images

    • Detection of human pre-mRNA cleavage factor I (59 kDa subunit) by Immunohistochemistry.
      Sample: formalin fixed, paraffin embedded section of human breast carcinoma.
      Antibody: ab84549 used at a dilution of 1/250.
      Detection: DAB staining.

    References

    ab84549 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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