Anti-Pregnancy zone protein antibody (ab122718)

Overview

  • Product nameAnti-Pregnancy zone protein antibody
  • Description
    Rabbit polyclonal to Pregnancy zone protein
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Protein Epitope Signature Tag antigen: QFSINTTSIS VNKLFVRVFT VHPNLCFHYS WVAEDHQGAQ HTANRVFSLS GSYIHLEPVA GTLPCGHTET ITAHYT, corresponding to amino acids 402 - 477 of Human Pregnancy zone protein. (P20742).

  • Positive control
    • Human pancreas tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • RelevanceIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • A1m antibody
    • C3 and PZP like alpha-2 macroglobulin domain containing protein 6 antibody
    • Complement component 3 and pregnancy zone protein like alpha 2 macroglobulin domain containing protein 6 antibody
    • CPAMD6 antibody
    • PZP antibody
    see all

Anti-Pregnancy zone protein antibody images

  • ab122718, at 1/10 dilution, staining Pregnancy zone protein in paraffin-embedded Human pancreas tissue by Immunohistochemistry.

References for Anti-Pregnancy zone protein antibody (ab122718)

ab122718 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"