Overview

  • Product name
  • Description
    Rabbit polyclonal to PRELP
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 125-155 of Human PRELP.

  • Positive control
    • Mouse heart tissue lysate. Breast carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab103868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 44 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May anchor basement membranes to the underlying connective tissue.
  • Tissue specificity
    Connective tissue.
  • Sequence similarities
    Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • Domain
    The basic amino-terminal Arg/Pro-rich binds heparin and heparan sulfate. Binds collagens type I and type II through its leucine-rich repeat domain.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 55 kDa leucine rich repeat protein of articular cartilage antibody
    • MST161 antibody
    • MSTP161 antibody
    • Prelp antibody
    • PRELP_HUMAN antibody
    • Prolargin antibody
    • Prolargin proteoglycan antibody
    • Proline arginine rich end leucine rich repeat protein antibody
    • Proline-arginine-rich end leucine-rich repeat protein antibody
    • Proline/arginine rich end leucine rich repeat protein antibody
    • SLRR2A antibody
    see all

Images

  • Anti-PRELP antibody (ab103868) at 1/50 dilution + Mouse heart tissue lysate at 15 µg

    Predicted band size : 44 kDa
  • ab103868, at 1/50, staining PRELP by Immunohistochemistry in breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

This product has been referenced in:
  • Tan HT  et al. Unravelling the proteome of degenerative human mitral valves. Proteomics 15:2934-44 (2015). WB ; Human . Read more (PubMed: 25914152) »
  • Loeser RF  et al. Disease progression and phasic changes in gene expression in a mouse model of osteoarthritis. PLoS One 8:e54633 (2013). IHC . Read more (PubMed: 23382930) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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