Overview

  • Product name
  • Description
    Rabbit polyclonal to PRG2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-222 of Human PRG2.

  • Positive control
    • Jurkat, K562, THP-1 and HL-60 whole cell lysates; Human hepatoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 79% PBS, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 25 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
  • Tissue specificity
    High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Developmental stage
    Levels of the proform increase in serum and placenta during pregnancy.
  • Post-translational
    modifications
    Nitrated.
  • Cellular localization
    Cytoplasmic vesicle > secretory vesicle. The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule and Secreted. The proform is secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BMPG antibody
    • EMBP antibody
    • Eosinophil granule major basic protein antibody
    • Eosinophil major basic protein antibody
    • MBP antibody
    • MBP1 antibody
    • Natural killer cell activator antibody
    • Pregnancy-associated major basic protein antibody
    • PRG 2 antibody
    • PRG2 antibody
    • PRG2_HUMAN antibody
    • Proteoglycan 2 antibody
    • Proteoglycan 2 bone marrow antibody
    • Proteoglycan 2 preproprotein antibody
    see all

Images

  • All lanes : Anti-PRG2 antibody (ab154655) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : K562 whole cell lysate
    Lane 3 : THP-1 whole cell lysate
    Lane 4 : HL-60 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 25 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling PRG2 with ab154655 at 1/500 dilution.

References

ab154655 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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