Anti-PRHOXNB antibody (ab122523)
Key features and details
- Rabbit polyclonal to PRHOXNB
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-PRHOXNB antibody -
Description
Rabbit polyclonal to PRHOXNB -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence, corresponding to amino acids 9-88 (MDLGEFVDVF GNATERCPLI AAAVWSQRPF SDLEDLEKHF FAFIDALAQS GQEGILRCHP DLAGSELQRG TLTAESQREQ) of Human PRHOXNB.
-
Positive control
- Human small intestine tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122523 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 1 - 4 µg/ml.
Recommend PFA Fixation and Triton X-100 treatment |
|
IHC-P |
1/850. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
Notes |
---|
ICC/IF
Use a concentration of 1 - 4 µg/ml. Recommend PFA Fixation and Triton X-100 treatment |
IHC-P
1/850. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. -
Tissue specificity
Apparently not expressed. -
Pathway
Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3. -
Sequence similarities
Belongs to the OHCU decarboxylase family. -
Cellular localization
Peroxisome. - Information by UniProt
-
Database links
- Entrez Gene: 646625 Human
- SwissProt: A6NGE7 Human
- Unigene: 705356 Human
-
Alternative names
- EG231903 antibody
- OHCU decarboxylase antibody
- Parahox neighbor antibody
see all
Images
-
Immunofluorescent staining of Human cell line U-251 MG shows positivity in plasma membrane and cytoplasm. Recommended concentration of ab122523 1-4 µg/ml. Cells treated with PFA/Triton X-100.
-
ab122523 at 1/850 dilution staining PRHOXNB in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab122523 has not yet been referenced specifically in any publications.