All tags Custom Services Custom services citations and references

Custom services citations and references

We have successfully collaborated on projects ranging from custom RabMAb development and polyclonal production to immunogen design.

Our clients include more than 550 institutions and 150 pharma and biotech companies. The following citations represent a partial list of custom RabMAb primary antibodies developed for research applications. 


References 

RabMAb advantage 

Low background

Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Journal of Clinical Microbiology 50: Feb 2012, 246-257

Ehehalt D, Lener B, Pircher H, et al

Detection of Human Papillomavirus Type 18 E7 Oncoprotein in Cervical Smears: a Feasibility Study.


Ideal for post-translational modification detection

Nature Methods 4: Jun 2007, 511-516

Allen JJ, Li M, Brinkworth CS, et al

A semisynthetic epitope for kinase substrates.


Cancer Res 67: 2007, 5362-5370

LeRoy PJ, Hunter JJ, Hoar KM, et al

Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser 558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity.


American Journal of Pathology 180: Apr 2012, 1386-1393

Mahajan K, Coppola D, Chen YA, et al

Ack1 tyrosine kinase activation correlates with pancreatic cancer progression.


Molecular Cell 40: Dec 2010, 893-904

Tao R, Coleman MC, Pennington JD, et al

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress.


Excellent for IHC usage

Genesis 49: July 2011, 673-680

Cuttler AS, LeClair RJ, Stohn JP, et al

Characterization of Pdgfrb-Cre Transgenic Mice Reveals Reduction of ROSA26 Reporter Activity in Remodeling Arteries.


Biology Open 000, 1–12 doi: 10.1242/bio.2012364

Goodman SL, Grote HJ, Wilm C

Matched rabbit monoclonal antibodies against av-series integrins reveal a novel avb3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.


Cancer Research 66: Nov, 2006, 10870-10877

Perk J, Gil-Bazo I, Chin Y, et al

Reassessment of Id1 Protein Expression in Human Mammary, Prostate, and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id1 Antibody.


High affinity

Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.

High specificity

Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.

Diverse/novel epitope recognition

J Virol 87: Sep 2013, 10232-43

Chen Y, Vaine M, Wallace A, et al

A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.


J Virol 87: Sep 2013, 10221-31

Pan R, Sampson JM, Chen Y, et al

Rabbit anti-HIV-1 monoclonal antibodies raised by immunization can mimic the antigen-binding modes of antibodies derived from HIV-1-infected humans.


Journal of Neuroscience Research 89: 2011, 822–832

Wu G, Sankaranarayanan S, Hsieh SH, et al

Decrease in Brain Soluble Amyloid Precursor Protein b (sAPPb) in Alzheimer’s Disease Cortex.


Fully validated in multiple applications

Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Journal of Virological Methods 174: Jun 2011, 99-109

Ou W, Delisle J, Konduru K, et al

Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins.


PLoS ONE 6: 2011, e21482

Shi C, Lu J, Wu W, et al

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway.



Ideal for use on mouse samples

Current Biology 19: Aug 2009, 1320-1326

Endoh-Yamagami S, Evangelista M, Wilson D, et al

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.


Cell 133: May 2008, 462-474

Erickson JR, Joiner ML, Guan X, et al

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation.


Anal. Biochem. 408: 2011, '321–327

Tan Z, Zhang J, Su Z, et al

Production of rabbit monoclonal antibodies against mouse embryonic stem cells and identification of pluripotency-associated surface antigens.

Application

Western blot

Nature Methods 4: Jun 2007, 511-516

Allen JJ, Li M, Brinkworth CS, et al

A semisynthetic epitope for kinase substrates.


Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Cell 133: May 2008, 462-474

Erickson JR, Joiner ML, Guan X, et al

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation.


Biology Open 000, 1–12 doi: 10.1242/bio.2012364

Goodman SL, Grote HJ, Wilm C

Matched rabbit monoclonal antibodies against av-series integrins reveal a novel avb3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.


American Journal of Pathology 180: Apr 2012, 1386-1393

Mahajan K, Coppola D, Chen YA, et al

Ack1 tyrosine kinase activation correlates with pancreatic cancer progression.


Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.


Virology 296: Jan 2010, 135-142

Ou W, King H, Delisle J, et al

Phenylalanines at positions 88 and 159 of Ebolavirus envelope glycoprotein differentially impact envelope function.


Journal of Virological Methods 174: Jun 2011, 99-109

Ou W, Delisle J, Konduru K, et al

Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins.


Cancer Research 66: Nov, 2006, 10870-10877

Perk J, Gil-Bazo I, Chin Y, et al

Reassessment of Id1 Protein Expression in Human Mammary, Prostate, and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id1 Antibody.


PLoS ONE 6: 2011, e21482

Shi C, Lu J, Wu W, et al

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway.


Journal of Neuroscience Research 89: 2011, 822–832

Wu G, Sankaranarayanan S, Hsieh SH, et al

Decrease in Brain Soluble Amyloid Precursor Protein b (sAPPb) in Alzheimer’s Disease Cortex.


Molecular Cell 40: Dec 2010, 893-904

Tao R, Coleman MC, Pennington JD, et al

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress.


Immunohistochemistry

Genesis 49: July 2011, 673-680

Cuttler AS, LeClair RJ, Stohn JP, et al

Characterization of Pdgfrb-Cre Transgenic Mice Reveals Reduction of ROSA26 Reporter Activity in Remodeling Arteries.


Biology Open 000, 1–12 doi: 10.1242/bio.2012364

Goodman SL, Grote HJ, Wilm C

Matched rabbit monoclonal antibodies against av-series integrins reveal a novel avb3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.


American Journal of Pathology 180: Apr 2012, 1386-1393

Mahajan K, Coppola D, Chen YA, et al

Ack1 tyrosine kinase activation correlates with pancreatic cancer progression.


Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.


Cancer Research 66: Nov, 2006, 10870-10877

Perk J, Gil-Bazo I, Chin Y, et al

Reassessment of Id1 Protein Expression in Human Mammary, Prostate, and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id1 Antibody.


​Immunocytochemistry/Immunofluorescence

Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Current Biology 19: Aug 2009, 1320-1326

Endoh-Yamagami S, Evangelista M, Wilson D, et al

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.


Cell 133: May 2008, 462-474

Erickson JR, Joiner ML, Guan X, et al

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation.


Cancer Res 67: 2007, 5362-5370

LeRoy PJ, Hunter JJ, Hoar KM, et al

Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser 558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity.


Journal of Virological Methods 174: Jun 2011, 99-109

Ou W, Delisle J, Konduru K, et al

Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins.


PLoS ONE 6: 2011, e21482

Shi C, Lu J, Wu W, et al

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway.


Immunoprecipitation 

Nature Methods 4: Jun 2007, 511-516

Allen JJ, Li M, Brinkworth CS, et al

A semisynthetic epitope for kinase substrates.


PLoS ONE 6: 2011, e21482

Shi C, Lu J, Wu W, et al

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway.


Anal. Biochem. 408: 2011, '321–327

Tan Z, Zhang J, Su Z, et al

Production of rabbit monoclonal antibodies against mouse embryonic stem cells and identification of pluripotency-associated surface antigens.


Molecular Cell 40: Dec 2010, 893-904

Tao R, Coleman MC, Pennington JD, et al

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress.


Flow cytometry 

Biology Open 000, 1–12 doi: 10.1242/bio.2012364

Goodman SL, Grote HJ, Wilm C

Matched rabbit monoclonal antibodies against av-series integrins reveal a novel avb3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.


Journal of Virological Methods 174: Jun 2011, 99-109

Ou W, Delisle J, Konduru K, et al

Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins.


ELISA – sandwich

Journal of Clinical Microbiology 50: Feb 2012, 246-257

Ehehalt D, Lener B, Pircher H, et al

Detection of Human Papillomavirus Type 18 E7 Oncoprotein in Cervical Smears: a Feasibility Study.


Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.


ELISA – other

Journal of Virological Methods 174: Jun 2011, 99-109

Ou W, Delisle J, Konduru K, et al

Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins.


Journal of Neuroscience Research 89: 2011, 822–832

Wu G, Sankaranarayanan S, Hsieh SH, et al

Decrease in Brain Soluble Amyloid Precursor Protein b (sAPPb) in Alzheimer’s Disease Cortex.


SISCAPA

​Functional

J Virol 87: Sep 2013, 10232-43

Chen Y, Vaine M, Wallace A, et al

A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.


J Virol 87: Sep 2013, 10221-31

Pan R, Sampson JM, Chen Y, et al

Rabbit anti-HIV-1 monoclonal antibodies raised by immunization can mimic the antigen-binding modes of antibodies derived from HIV-1-infected humans.

Research area

Cancer

Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Journal of Clinical Microbiology 50: Feb 2012, 246-257

Ehehalt D, Lener B, Pircher H, et al

Detection of Human Papillomavirus Type 18 E7 Oncoprotein in Cervical Smears: a Feasibility Study.


Cancer Res 67: 2007, 5362-5370

LeRoy PJ, Hunter JJ, Hoar KM, et al

Localization of Human TACC3 to Mitotic Spindles Is Mediated by Phosphorylation on Ser 558 by Aurora A: A Novel Pharmacodynamic Method for Measuring Aurora A Activity.


Cancer Research 66: Nov, 2006, 10870-10877

Perk J, Gil-Bazo I, Chin Y, et al

Reassessment of Id1 Protein Expression in Human Mammary, Prostate, and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id1 Antibody.


Molecular Cell 40: Dec 2010, 893-904

Tao R, Coleman MC, Pennington JD, et al

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress.


Cardiovascular

Genesis 49: July 2011, 673-680

Cuttler AS, LeClair RJ, Stohn JP, et al

Characterization of Pdgfrb-Cre Transgenic Mice Reveals Reduction of ROSA26 Reporter Activity in Remodeling Arteries.


Cell biology

PLoS ONE 6: 2011, e21482

Shi C, Lu J, Wu W, et al

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway.

Developmental biology

Drug discovery

Epigenetics & nuclear signaling

Immunology

J Virol 87: Sep 2013, 10232-43

Chen Y, Vaine M, Wallace A, et al

A novel rabbit monoclonal antibody platform to dissect the diverse repertoire of antibody epitopes for HIV-1 Env immunogen design.


J Virol 87: Sep 2013, 10221-31

Pan R, Sampson JM, Chen Y, et al

Rabbit anti-HIV-1 monoclonal antibodies raised by immunization can mimic the antigen-binding modes of antibodies derived from HIV-1-infected humans.


Metabolism

Microbiology

Virology 409: Jan 2011, 54-68

Dreier K, Scheiden R, Lener B, et al

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.


Virology 296: Jan 2010, 135-142

Ou W, King H, Delisle J, et al

Phenylalanines at positions 88 and 159 of Ebolavirus envelope glycoprotein differentially impact envelope function.


Neuroscience

Journal of Alzheimer’s Disease 23: 2011, 293-305

Miller DL, Potempska A, Wegiel J, et al

High-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides Amyloid-β40 and Amyloid-β42.


Journal of Neuroscience Research 89: 2011, 822–832

Wu G, Sankaranarayanan S, Hsieh SH, et al

Decrease in Brain Soluble Amyloid Precursor Protein b (sAPPb) in Alzheimer’s Disease Cortex.


Signal transduction

Nature Methods 4: Jun 2007, 511-516

Allen JJ, Li M, Brinkworth CS, et al

A semisynthetic epitope for kinase substrates.


Current Biology 19: Aug 2009, 1320-1326

Endoh-Yamagami S, Evangelista M, Wilson D, et al

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.


Stem cells

Anal. Biochem. 408: 2011, '321–327

Tan Z, Zhang J, Su Z, et al

Production of rabbit monoclonal antibodies against mouse embryonic stem cells and identification of pluripotency-associated surface antigens.

*****************************************************


ACS Chemical Neuroscience (2013) 4: 613-623

McLean D, Cooke MJ, Albay R III et al

Positron Emission Tomography Imaging of Fibrillar Parenchymal and Vascular Amyloid‑β in TgCRND8 Mice




The Journal of Pharmacology and Experimental Therapeutics, 319: Oct, 2006, 192-198

Klionsky L, Tamir R, Holzinger B, et al

A Polyclonal Antibody to the Prepore Loop of Transient Receptor Potential Vanilloid Type 1 Blocks Channel Activation.


Cardiovasc Res 96: Oct 2012, 109 - 119

Sauls K, de Vlaming A, Harris BS, et al

Developmental basis for filamin-A-associated myxomatous mitral valve disease.


Journal of Immunological Methods 353: 2010, 49–61

Schoenherr RM, Zhao L, Whiteaker JR, et al

Automated screening of monoclonal antibodies for SISCAPA assays using a magnetic bead processor and liquid chromatography-selected reaction monitoring-mass spectrometry.