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While mouse monoclonals can also be highly specific, subtle changes in epitopes are often not recognizable by the mouse immune system. On the contrary, the rabbit immune system is capable of recognizing subtle differences, thus enabling the generation of antibodies for epitopes that distinguish one protein from another. The example below demonstrates the high specificity of our anti-Progesterone RabMAb primary antibody, as it does not cross-react with closely related analogues of progesterone.
The superior specificity of RabMAb primary antibodies allows for generation of high quality antibodies which recognize subtle changes in epitopes, such as those created upon protein cleavage or between closely related proteins.