Anti-Prion protease resistant protein 27-30 antibody (ab187555)

Overview

  • Product name
    Anti-Prion protease resistant protein 27-30 antibody
  • Description
    Rabbit Polyclonal to Prion protease resistant protein 27-30
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Sheep, Goat, Hamster, Chimpanzee, Mink, Non human primates, Cynomolgus monkey, Macaque monkey, Rhesus monkey, Deer, Chinese hamster, Orangutan
  • Immunogen

    Recombinant full length protein corresponding to Human Prion protease resistant protein 27-30 aa 23-230.
    Database link: P04156

  • Positive control
    • SKOV3, Mouse brain and Mouse kidney cell extracts.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab187555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 27 kDa.
IHC-P 1/50 - 1/200.

Target

  • Relevance
    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Cellular localization
    Cell Membrane; lipid-anchor; GPI-anchor
  • Database links
  • Alternative names
    • ASCR antibody
    • CD230 antibody
    • CD230 antigen antibody
    • CJD antibody
    • Creutzfeld Jakob disease antibody
    • Fatal familial insomnia antibody
    • Gerstmann Strausler Scheinker syndrome antibody
    • GSS antibody
    • MGC26679 antibody
    • Prion protease resistant protein antibody
    • Prion PrP antibody
    • PRIP antibody
    • PRNP antibody
    • PRP antibody
    • PrP 27 30 antibody
    • PrP27 30 antibody
    • PrP33 35C antibody
    • PrPc antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling Prion protease resistant protein 27-30 with ab187555 at 1/100. Magnification: 400x.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling Prion protease resistant protein 27-30 with ab187555 at 1/100. Magnification: 400x.
  • All lanes : Anti-Prion protease resistant protein 27-30 antibody (ab187555) at 1/500 dilution

    Lane 1 : SKOV3 cell extract
    Lane 2 : Mouse brain cell extract
    Lane 3 : Mouse kidney cell extract


    Predicted band size : 27 kDa

References

ab187555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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