Overview

  • Product nameAnti-proANP antibody
    See all proANP primary antibodies
  • Description
    Sheep polyclonal to proANP
  • SpecificitySynthetic human proANP (aa 31-67). There were no cross reactivities obtained with human proANP (aa 67-98) and human proANP (aa 1-30).
  • Tested applicationsSuitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Cat, Dog, Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide:

    EVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQR

    , corresponding to amino acids 31-67 of Human proANP.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab14349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA 1/2000.

Target

  • FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Involvement in diseaseAtrial standstill 2
    Atrial fibrillation, familial, 6
  • Sequence similaritiesBelongs to the natriuretic peptide family.
  • Post-translational
    modifications
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANF antibody
    • ANF_HUMAN antibody
    • ANP antibody
    • ATFB6 antibody
    • Atrial natriuretic factor antibody
    • Atrial natriuretic peptide antibody
    • Atriopeptin antibody
    • ATRST2 antibody
    • Cardiodilatin antibody
    • Cardiodilatin-related peptide antibody
    • Cardionatrin antibody
    • CDD ANF antibody
    • CDD antibody
    • CDD-ANF antibody
    • CDP antibody
    • Natriuretic peptide A antibody
    • Natriuretic peptide precursor A antibody
    • Natriuretic peptides A antibody
    • NPPA antibody
    • PND antibody
    • Prepronatriodilatin antibody
    • Pronatriodilatin antibody
    see all

References for Anti-proANP antibody (ab14349)

ab14349 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab14349.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"