Anti-Proapoptotic Caspase Adaptor Protein antibody (ab67021)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab67021 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 17 kDa (predicted molecular weight: 20 kDa).

Target

  • Relevance
    Proapoptotic Caspase Adaptor Protein associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity By similarity. Isoform 2 may be involved in regulation of apoptosis.
  • Cellular localization
    Isoform 1: Endoplasmic reticulum Isoform 2: Cytoplasm. Note: Diffuse granular localization in the cytoplasm surrounding the nucleus.
  • Database links
  • Alternative names
    • MZB1 antibody
    • Caspase 2 binding protein antibody
    • FLJ32987 antibody
    • HSPC190 antibody
    • Marginal zone B and B1 cell specific protein antibody
    • MEDA 7 antibody
    • Mesenteric estrogen dependent adipose 7 antibody
    • Mesenteric oestrogen dependent adipose gene 7 antibody
    • MGC29506 antibody
    • PACAP antibody
    • pERp1 antibody
    • Plasma cell-induced ER protein 1 antibody
    • Plasma cell-induced resident endoplasmic reticulum protein antibody
    • Plasma cell-induced resident ER protein antibody
    • Proapoptotic caspase adapter protein antibody
    see all

Images

  • All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody (ab67021) at 1/500 dilution

    Lane 1 : Transfected 293T cell lysate
    Lane 2 : non Transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 20 kDa
    Observed band size : 17 kDa (why is the actual band size different from the predicted?)

References

ab67021 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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