Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308)

Overview

  • Product nameAnti-Proapoptotic Caspase Adaptor Protein antibody
    See all Proapoptotic Caspase Adaptor Protein primary antibodies
  • Description
    Rabbit polyclonal to Proapoptotic Caspase Adaptor Protein
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within the amino acids 1-189 of Human Proapoptotic Caspase Adaptor Protein.

  • Positive control
    • MOLT4 or Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 21 kDa.

Target

  • RelevanceProapoptotic Caspase Adaptor Protein associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity By similarity. Isoform 2 may be involved in regulation of apoptosis.
  • Cellular localizationIsoform 1: Endoplasmic reticulum Isoform 2: Cytoplasm. Note: Diffuse granular localization in the cytoplasm surrounding the nucleus.
  • Database links
  • Alternative names
    • MZB1 antibody
    • Caspase 2 binding protein antibody
    • FLJ32987 antibody
    • HSPC190 antibody
    • Marginal zone B and B1 cell specific protein antibody
    • MEDA 7 antibody
    • Mesenteric estrogen dependent adipose 7 antibody
    • Mesenteric oestrogen dependent adipose gene 7 antibody
    • MGC29506 antibody
    • PACAP antibody
    • pERp1 antibody
    • Plasma cell-induced ER protein 1 antibody
    • Plasma cell-induced resident endoplasmic reticulum protein antibody
    • Plasma cell-induced resident ER protein antibody
    • Proapoptotic caspase adapter protein antibody
    see all

Anti-Proapoptotic Caspase Adaptor Protein antibody images

  • All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308) at 1/1000 dilution

    Lane 1 : MOLT4 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 21 kDa

References for Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308)

This product has been referenced in:
  • Kocevar N  et al. Proteomic analysis of gastric cancer and immunoblot validation of potential biomarkers. World J Gastroenterol 18:1216-28 (2012). WB ; Human . Read more (PubMed: 22468085) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Tissue lysate - whole (Stomach)
Loading amount 30 µg
Specification Stomach
Gel Running Conditions Reduced Denaturing (12 %)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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Submitted Jul 13 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"