Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308)

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Overview

  • Product name
    Anti-Proapoptotic Caspase Adaptor Protein antibody
    See all Proapoptotic Caspase Adaptor Protein primary antibodies
  • Description
    Rabbit polyclonal to Proapoptotic Caspase Adaptor Protein
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within the amino acids 1-189 of Human Proapoptotic Caspase Adaptor Protein.

  • Positive control
    • MOLT4 or Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 21 kDa.

Target

  • Relevance
    Proapoptotic Caspase Adaptor Protein associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity By similarity. Isoform 2 may be involved in regulation of apoptosis.
  • Cellular localization
    Isoform 1: Endoplasmic reticulum Isoform 2: Cytoplasm. Note: Diffuse granular localization in the cytoplasm surrounding the nucleus.
  • Database links
    • Alternative names
      • MZB1 antibody
      • Caspase 2 binding protein antibody
      • FLJ32987 antibody
      • HSPC190 antibody
      • Marginal zone B and B1 cell specific protein antibody
      • MEDA 7 antibody
      • Mesenteric estrogen dependent adipose 7 antibody
      • Mesenteric oestrogen dependent adipose gene 7 antibody
      • MGC29506 antibody
      • PACAP antibody
      • pERp1 antibody
      • Plasma cell-induced ER protein 1 antibody
      • Plasma cell-induced resident endoplasmic reticulum protein antibody
      • Plasma cell-induced resident ER protein antibody
      • Proapoptotic caspase adapter protein antibody
      see all

    Images

    • Western blot - Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308)
      Western blot - Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308)
      All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308) at 1/1000 dilution

      Lane 1 : MOLT4 whole cell lysate
      Lane 2 : Raji whole cell lysate

      Lysates/proteins at 30 µg per lane.

      Predicted band size: 21 kDa



      15% SDS PAGE

    References

    This product has been referenced in:
    • Kocevar N  et al. Proteomic analysis of gastric cancer and immunoblot validation of potential biomarkers. World J Gastroenterol 18:1216-28 (2012). WB ; Human . Read more (PubMed: 22468085) »

    See 1 Publication for this product

    Publishing research using ab96308? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    1 Review or Q&A

    10
    Votes: Highest First

    Western blot abreview for Anti-Proapoptotic Caspase Adaptor Protein antibody

     Excellent
    Abreviews
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Tissue lysate - whole (Stomach)
    Loading amount
    30 µg
    Specification
    Stomach
    Gel Running Conditions
    Reduced Denaturing (12 %)
    Blocking step
    Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Read More
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    Submitted Jul 13 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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