Anti-proBNP antibody [24E11] (HRP) (ab13123)

Overview

  • Product nameAnti-proBNP antibody [24E11] (HRP)
    See all proBNP primary antibodies
  • Description
    Mouse monoclonal [24E11] to proBNP (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: ELISA, WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    RGHRKMVLYTLRAPR

    , corresponding to amino acids 61 - 76 of Human proBNP.

  • General notesImmunoglobulin concentrations vary from batch to batch. Please contact technical services for the latest information.

Properties

Applications

Our Abpromise guarantee covers the use of ab13123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 13 kDa.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [15F11] to proBNP (ab13115). Can be used as detection antibody in conjunction with recommended pair. Recognises the antigen in blood of patients with heart faliure, unstable angina and myocardial infarction.

Target

  • FunctionCardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Tissue specificityBrain and also in atria, but at much lower levels than ANP.
  • Sequence similaritiesBelongs to the natriuretic peptide family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANFB_HUMAN antibody
    • BNP antibody
    • BNP(1-32) antibody
    • BNP(5-29) antibody
    • BNP-32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Gamma-brain natriuretic peptide antibody
    • Natriuretic peptide precursor B antibody
    • nppb antibody
    • NT proBNP antibody
    see all

References for Anti-proBNP antibody [24E11] (HRP) (ab13123)

ab13123 has not yet been referenced specifically in any publications.

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I have to confirm that do not have any pro-BNP antibodies that are tested and guaranteed for rat.

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