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Epigenetics

Epigenetics

Our guide to histone modifications

Histones pack and order the DNA into nucleosomes, the building blocks of chromatin. Each nucleosome contains two subunits each of histones, known as the core histones. They are characterized by a large number of post-translational modifications. Learn more.

Sodium butyrate (ab120948)

Description:
Histone deacetylase inhibitor
Purity:
> 98%

5-Aza-2'-deoxycytidine (Decitabine) (ab120842)

Description:
Potent DNMT1 inhibitor. Induces DNA hypomethylation.
Purity:
> 99%

Nicotinamide (ab120864)

Description:
Amide form of vitamin B3
Purity:
> 99%

RG 108 (ab141013)

Description:
Novel, non-nucleoside DNA methyltransferase inhibitor (DNMT)
Purity:
> 99%

Trichostatin A (ab120850)

Description:
Potent, selective histone deacetylase inhibitor
Purity:
> 98%

(+)-JQ1 (ab141498)

Description:
Potent, selective and cell-permeable BET bromodomain inhibitor
Purity:
> 99%

Bisdemethoxycurcumin (ab120976)

Description:
Apoptotic anticancer, anti-inflammatory and antioxidant curcuminoid
Purity:
> 98%

Butyrolactone 3 (ab141255)

Description:
Histone acetyltransferase Gcn5 inhibitor
Purity:
> 99%

C 646, p300/CBP Inhibitor (ab142163)

Description:
Cell-permeable, competitive, selective, potent p300/CBP HAT inhibitor
Purity:
> 98%

Hydralazine hydrochloride (ab120863)

Description:
DNA methylation inhibitor. Antihypertensive agent.
Purity:
> 99%