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Epigenetics

Epigenetics

Chromatin remodelling and transcription

This poster, in collaboration with Nature, Jerry Workman and Vikki Weake, highlights the chromatin remodelling mechanisms within the transcription cycle.

Sodium butyrate (ab120948)

Description:
Histone deacetylase inhibitor
Purity:
> 98%

5-Aza-2'-deoxycytidine (Decitabine) (ab120842)

Description:
Potent DNMT1 inhibitor. Induces DNA hypomethylation.
Purity:
> 99%

Temozolomide (ab141055)

Description:
DNA alkylating/methylating chemotherapeutic agent
Purity:
> 99%

Trichostatin A (ab120850)

Description:
Potent, selective histone deacetylase inhibitor
Purity:
> 98%

Nicotinamide (ab120864)

Description:
Amide form of vitamin B3
Purity:
> 99%

Sodium 4-phenylbutyrate (ab141253)

Description:
Histone deacetylase inhibitor
Purity:
> 99%

Butyrolactone 3 (ab141255)

Description:
Histone acetyltransferase Gcn5 inhibitor
Purity:
> 99%

Bisdemethoxycurcumin (ab120976)

Description:
Apoptotic anticancer, anti-inflammatory and antioxidant curcuminoid
Purity:
> 98%

Hydralazine hydrochloride (ab120863)

Description:
DNA methylation inhibitor. Antihypertensive agent.
Purity:
> 99%

RG 108 (ab141013)

Description:
Novel, non-nucleoside DNA methyltransferase inhibitor (DNMT)
Purity:
> 99%