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Epigenetics

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Epigenetics

Epigenetics

Chromatin remodelling and transcription

This poster, in collaboration with Nature, Jerry Workman and Vikki Weake, highlights the chromatin remodelling mechanisms within the transcription cycle.

(+)-Abscisic acid (ab120860)

Description:
Phytohormone; produced by a variety of cells in humans and animals
Purity:
> 99%

(+)-JQ1 (ab141498)

Description:
Potent, selective and cell-permeable BET bromodomain inhibitor
Purity:
> 99%

1-Naphthohydroxamic acid (ab144502)

Description:
Potent, cell-permeable and selective HDAC8 inhibitor
Purity:
> 99%

3-Deazaneplanocin A (ab142215)

Description:
Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor
Purity:
> 98%

5-Aza-2'-deoxycytidine (Decitabine) (ab120842)

Description:
Potent DNMT1 inhibitor. Induces DNA hypomethylation.
Purity:
> 99%

5-Azacytidine (ab142744)

Description:
Potent DNMT1 inhibitor. Induces DNA hypomethylation.
Purity:
> 99%

5-Chloro-2-methyl-3-isothiazolone (ab144735)

Description:
PCAF histone acetyltransferase inhibitor

AGK2 (ab142073)

Description:
Selective reversible cell-permeable sirtuin2 (SIRT2) inhibitor
Purity:
> 95%

AK-1 (ab144549)

Description:
Cell-permeable SIRT2 inhibitor
Purity:
> 99%

AK-7 (ab142128)

Description:
Selective, centrally active SIRT2 inhibitor
Purity:
> 98%