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Signal transduction
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Biochemicals

Guidelines for small-molecule inhibitors

A few hints and tips on small molecule inhibitor best practice to get you started. From negative controls to dose dependent effects - a beginners guide.

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Forskolin (ab120058)

Description:
Adenylyl cyclase activator
Purity:
> 98%
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PD 98059 (ab120234)

Description:
MEK1 inhibitor
Purity:
> 99%
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LY 294002 (ab120243)

Description:
PI3-kinase inhibitor
Purity:
> 99%

AMD3100 octahydrochloride (ab120718)

Description:
Highly selective CXCR4 antagonist
Purity:
> 99%

Okadaic acid (ab120375)

Description:
PP1 and PP2A inhibitor

SB 203580 (ab120162)

Description:
p38 MAPK inhibitor
Purity:
> 99%

SP600125 (ab120065)

Description:
JNK inhibitor
Purity:
> 98%
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U0126 (ab120241)

Description:
Selective MKK inhibitor
Purity:
> 98%
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Apocynin (ab120615)

Description:
Selective NADPH-oxidase inhibitor
Purity:
> 99%
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Stattic (ab120952)

Description:
Selective STAT3 inhibitor
Purity:
> 99%