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Cancer
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cancer

c-Jun N-terminal kinase (JNK) signalling

Activation of JNK1/2 MAPK occurs following osmotic stress, UV irradiation, cytokine withdrawal, mitogenic signalling and MTA treatment.

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Forskolin (ab120058)

Description:
Adenylyl cyclase activator
Purity:
> 98%
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Y-27632 dihydrochloride (ab120129)

Description:
Selective Rho kinase inhibitor
Purity:
> 99%
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Z-VAD-FMK (ab120382)

Description:
Irreversible general caspase inhibitor
Purity:
> 97%
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Cycloheximide (ab120093)

Description:
Protein synthesis inhibitor
Purity:
> 98%
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Ionomycin Ca2+ Salt (ab120116)

Description:
Ca2+ ionophore
Purity:
> 99%
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LY 294002 (ab120243)

Description:
PI3-kinase inhibitor
Purity:
> 99%
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U0126 (ab120241)

Description:
Selective MKK inhibitor
Purity:
> 98%
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Ryanodine (ab120083)

Description:
Ca2+ release modulator
Purity:
> 98%
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(±)-Blebbistatin (ab120425)

Description:
Potent, selective, inhibitor of myosin II
Purity:
> 99%

FCCP (ab120081)

Description:
Potent mitochondrial oxidative phosphorylation uncoupler
Purity:
> 99%
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