For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
If you continue without changing your settings we'll assume you’re happy.
If incorrect, please enter your country into the box below, to view site information related to your location.
Don't have an account?
We offer world-leading antibody development platforms based on a proprietary RabMAb® rabbit monoclonal platform, a phase display platform (AxioMx), and a next-generation sequencing platform (NGS-RabMAb®)
Custom product and licensing overview
We can help with downstream assay development for single-wash ELISA assays (SimpleStep ELISA®) and multiplex assays (FirePlex®)
AxioMx phage display technology
Visit protocols and troubleshooting or check them out using the Abcam app for iPhone
Protocols and troubleshooting
Full event breakdown with abstracts, speakers, registration and more
View global event calendar
View all pathways
View all interactive pathways
p53 can inhibit cell cycle progression, maintain genomic stability through DNA repair & regulate the process of angiogenesis. It can also stimulate a network of signals through extrinsic & intrinsic pathways & induce senescence in response to high levels of stress.