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Neuroscience

The role of GSK3 in insulin, Wnt, Reelin & Hedgehog signaling.

Read an overview of GSK3 functions in the insulin, Wnt, Reelin & Hedgehog signaling pathways as well as in neurodegenerative & neurological diseases.

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GANT 61 (ab120904)

Description:
Selective GLI1 and 2 inhibitor
Purity:
> 98%
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Jervine (ab120815)

Description:
Smoothened inhibitor
Purity:
> 98%

Cyclopamine-KAAD (ab142146)

Description:
Cell-permeable Smo/Hh/GLI1 signaling inhibitor
Purity:
> 80%

Purmorphamine (ab120933)

Description:
Smoothened receptor agonist
Purity:
> 98%

SANT-1 (ab141483)

Description:
Potent smoothened and hedgehog signaling antagonist
Purity:
> 98%

SANT-2 (ab141481)

Description:
Potent smoothened receptor antagonist
Purity:
> 95%

PF-5274857 (ab141996)

Description:
Potent, selective Smoothened (Smo) antagonist.
Purity:
> 99%
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