Overview

  • Product nameAnti-Profilin 2 antibody
    See all Profilin 2 primary antibodies
  • Description
    Mouse monoclonal to Profilin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: QSITPIEIDM IVGKDREGFF TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRAL VIVMGKEGVH GGTLNKKAYE LALYLRRSDV , corresponding to amino acids 41-141 of Human Profilin 2

Properties

Applications

Our Abpromise guarantee covers the use of ab55611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
    • Tissue specificityHighly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
    • Sequence similaritiesBelongs to the profilin family.
    • Cellular localizationCytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • D3S1319E antibody
      • PFL antibody
      • PFN 2 antibody
      • Pfn2 antibody
      • PROF2_HUMAN antibody
      • Profilin II antibody
      • Profilin-2 antibody
      • Profilin2 antibody
      • ProfilinII antibody
      see all

    Anti-Profilin 2 antibody images



    • Predicted band size : 15 kDa
      Profilin 2 antibody (ab55611) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-Profilin 2 antibody (ab55611)

    This product has been referenced in:
    • Liu HP  et al. Proteome-wide Dysregulation by PRA1 Depletion Delineates a Role of PRA1 in Lipid Transport and Cell Migration. Mol Cell Proteomics 10:M900641MCP200 (2011). WB ; Human . Read more (PubMed: 20592422) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab55611.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"