Anti-Prohibitin antibody (ab115669)

Overview

  • Product nameAnti-Prohibitin antibody
    See all Prohibitin primary antibodies
  • Description
    Rabbit polyclonal to Prohibitin
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region from the C-terminus of Human Prohibitin.

  • Positive control
    • Human Kidney tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab115669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500. Predicted molecular weight: 30 kDa.
IHC-P 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionProhibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
  • Tissue specificityWidely expressed in different tissues.
  • Sequence similaritiesBelongs to the prohibitin family.
  • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Epididymis luminal protein 215 antibody
    • Epididymis secretory sperm binding protein Li 54e antibody
    • HEL 215 antibody
    • HEL S 54e antibody
    • PHB antibody
    • PHB_HUMAN antibody
    • PHB1 antibody
    • Prohibitin antibody
    see all

Anti-Prohibitin antibody images

  • Human Kidney (formalin-fixed, paraffin-embedded) stained with ab115669 at 1/50 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-Prohibitin antibody (ab115669)

ab115669 has not yet been referenced specifically in any publications.

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