Anti-Prohibitin antibody (ab70672)

Overview

  • Product nameAnti-Prohibitin antibody
    See all Prohibitin primary antibodies
  • Description
    Rabbit polyclonal to Prohibitin
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to near C terminus of human Prohibitin protein.

  • Positive control
    • Human heart.

Properties

Applications

Our Abpromise guarantee covers the use of ab70672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesIHC-P: 1/100 for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    WB: Use at an assay dependent dilution. Predicted molecular weight: 30 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProhibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
    • Tissue specificityWidely expressed in different tissues.
    • Sequence similaritiesBelongs to the prohibitin family.
    • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
    • Cellular localizationMitochondrion inner membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Epididymis luminal protein 215 antibody
      • Epididymis secretory sperm binding protein Li 54e antibody
      • HEL 215 antibody
      • HEL S 54e antibody
      • PHB antibody
      • PHB_HUMAN antibody
      • PHB1 antibody
      • Prohibitin antibody
      see all

    Anti-Prohibitin antibody images

    • ab70672, at 1/100 dilution, staining Prohibitin in formalin fixed, paraffin embedded human heart tissue by immunohistochemistry.

    References for Anti-Prohibitin antibody (ab70672)

    ab70672 has not yet been referenced specifically in any publications.

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