Anti-Prohibitin antibody [II-14-10], prediluted (ab59773)

Overview

  • Product nameAnti-Prohibitin antibody [II-14-10], prediluted
    See all Prohibitin primary antibodies
  • Description
    Mouse monoclonal [II-14-10] to Prohibitin, prediluted
  • SpecificityThis antibody is specific to 30 kD protein known as Prohibitin.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Pig
  • Immunogen

    Recombinant purified full length protein (Rat)

  • Positive control
    • Heart tissue.

Applications

Our Abpromise guarantee covers the use of ab59773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC-P: This antibody has been pretitered. High temperature treatment of formalin-fixed tissue sections using 10 mM citrate buffer, pH 6.0 must be performed prior to the immunostaining.
    IHC-Fr: This antibody has been pretitered.

    We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.

    Not yet tested in other applications.
  • Target

    • FunctionProhibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
    • Tissue specificityWidely expressed in different tissues.
    • Sequence similaritiesBelongs to the prohibitin family.
    • Developmental stageLevels of expression in fibroblasts decrease heterogeneously during cellular aging.
    • Cellular localizationMitochondrion inner membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Epididymis luminal protein 215 antibody
      • Epididymis secretory sperm binding protein Li 54e antibody
      • HEL 215 antibody
      • HEL S 54e antibody
      • PHB antibody
      • PHB_HUMAN antibody
      • PHB1 antibody
      • Prohibitin antibody
      see all

    References for Anti-Prohibitin antibody [II-14-10], prediluted (ab59773)

    ab59773 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"