Anti-Prohibitin antibody, prediluted (ab74539)

Overview

  • Product name
    Anti-Prohibitin antibody, prediluted
    See all Prohibitin primary antibodies
  • Description
    Rabbit polyclonal to Prohibitin, prediluted
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to near the C-terminus of human Prohibitin protein

  • Positive control
    • Human Heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab74539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Ready-to-use for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
    • Tissue specificity
      Widely expressed in different tissues.
    • Sequence similarities
      Belongs to the prohibitin family.
    • Developmental stage
      Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
    • Cellular localization
      Mitochondrion inner membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Epididymis luminal protein 215 antibody
      • Epididymis secretory sperm binding protein Li 54e antibody
      • HEL 215 antibody
      • HEL S 54e antibody
      • PHB antibody
      • PHB_HUMAN antibody
      • PHB1 antibody
      • Prohibitin antibody
      see all

    Images

    • ab74539 staining Prohibitin in Human Heart by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

    References

    ab74539 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Thank you very much for your patience.

    I have hear back now from the laboratories in regards to the potential crossreaction of the prohibitin antibodies with T. brucei. Unfortunately none of these antibodies seems to be likely to crossreact w...

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