Anti-Prokineticin 1 antibody [MM0043-2L13] (ab72807)

Overview

  • Product name
    Anti-Prokineticin 1 antibody [MM0043-2L13]
    See all Prokineticin 1 primary antibodies
  • Description
    Mouse monoclonal [MM0043-2L13] to Prokineticin 1
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Human recombinant full length Prokineticin 1 protein

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    MM0043-2L13
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab72807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 12 kDa.
ELISA Use at an assay dependent dilution.
IHC-P 1/50 - 1/100.

Target

  • Function
    Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
  • Tissue specificity
    Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.
  • Sequence similarities
    Belongs to the AVIT (prokineticin) family.
  • Developmental stage
    In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Black mamba toxin related protein antibody
    • EG VEGF antibody
    • EG-VEGF antibody
    • EGVEGF antibody
    • Endocrine-gland-derived vascular endothelial growth factor antibody
    • Mambakine antibody
    • PK1 antibody
    • PRK1 antibody
    • PROK1 antibody
    • PROK1_HUMAN antibody
    • Prokineticin-1 antibody
    see all

Anti-Prokineticin 1 antibody [MM0043-2L13] images

  • ab72807 at 1/100 dilution, staining Prokineticin 1 in human placenta tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

References for Anti-Prokineticin 1 antibody [MM0043-2L13] (ab72807)

ab72807 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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