Overview

  • Product nameAnti-PROP1 antibody
    See all PROP1 primary antibodies
  • Description
    Rabbit polyclonal to PROP1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Sheep, Horse, Chicken, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 177-226 (SQPSTGGAFA LSHQSEDWYP TLHPAPAGHL PCPPPPPMLP LSLEPSKSWN) of Human PROP1 (NP_006252).

  • Positive control
    • Colo205 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94500 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevancePROP1 belongs to the paired homeobox family. It contains one homeobox DNA-binding domain. PROP1 is possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. It is expressed specifically in embryonic pituitary. Defects in PROP1 are a cause of combined pituitary hormone deficiency (CPHD). This is characterized by impaired production of growth hormone (GH) and one or more of the other five anterior pituitary hormones.
  • Cellular localizationNucleus
  • Database links
  • Alternative names
    • CPHD2 antibody
    • Homeobox protein prophet of Pit 1 antibody
    • OTTHUMP00000161487 antibody
    • paired-like homeodomain transcription factor antibody
    • Pituitary specific homeodomain factor antibody
    • PROP 1 antibody
    • PROP paired like homeobox 1 antibody
    • prophet of Pit1 antibody
    see all

Anti-PROP1 antibody images

  • Anti-PROP1 antibody (ab94500) at 1 µg/ml (in 5% skim milk / PBS buffer) + Colo205 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 25 kDa

References for Anti-PROP1 antibody (ab94500)

This product has been referenced in:
  • Hu Y  et al. Circulating microRNA profiles and the identification of miR-593 and miR-511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency. Int J Mol Med 35:358-66 (2015). WB ; Human . Read more (PubMed: 25434367) »

See 1 Publication for this product

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