Overview

  • Product name
    Anti-Properdin antibody [10C5]
    See all Properdin primary antibodies
  • Description
    Mouse monoclonal [10C5] to Properdin
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    10C5
  • Myeloma
    x63-Ag8.653
  • Isotype
    IgG1
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: 1/10000.
    WB: Use at an assay dependent dilution. Predicted molecular weights: 25, 56 (reduced) and 220 kDa (unreduced).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
    • Involvement in disease
      Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
    • Sequence similarities
      Contains 6 TSP type-1 domains.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BFD antibody
      • CFP antibody
      • Complement factor P antibody
      • Complement factor properdin antibody
      • Factor P antibody
      • PFC antibody
      • PFD antibody
      • PROP_HUMAN antibody
      • Properdin antibody
      • Properdin P factor complement antibody
      see all

    References

    ab17780 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab17780.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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