Overview

  • Product nameAnti-Properdin antibody [10C5]
    See all Properdin primary antibodies
  • Description
    Mouse monoclonal [10C5] to Properdin
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number10C5
  • Myelomax63-Ag8.653
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: 1/10000.
    WB: Use at an assay dependent dilution. Predicted molecular weights: 25, 56 (reduced) and 220 kDa (unreduced).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionA positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
    • Involvement in diseaseDefects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
    • Sequence similaritiesContains 6 TSP type-1 domains.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BFD antibody
      • CFP antibody
      • Complement factor P antibody
      • Complement factor properdin antibody
      • Factor P antibody
      • PFC antibody
      • PFD antibody
      • PROP_HUMAN antibody
      • Properdin antibody
      • Properdin P factor complement antibody
      see all

    References for Anti-Properdin antibody [10C5] (ab17780)

    ab17780 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab17780.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"