Overview

  • Product name
    Prostaglandin A2
  • Description
    Endogenous metabolite derived from arachidonic acid
  • Biological description
    Endogenous metabolite derived from arachidonic acid. Plays a vital role in the induction of apoptosis. Blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Additionally acts as a vasodilator with natriuretic properties.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Lee SY  et al. Prostaglandin A2 activates intrinsic apoptotic pathway by direct interaction with mitochondria in HL-60 cells. Prostaglandins Other Lipid Mediat 91:30-7 (2010). Read more (PubMed: 20044024) »
  • Joubert A  et al. Influence of prostaglandin A2 on Bax, Bcl-2 and PCNA expression in MCF-7 cells. Biomed Res 27:157-62 (2006). Read more (PubMed: 16971768) »
  • Hitomi M  et al. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation. J Biol Chem 271:9376-83 (1996). Read more (PubMed: 8621603) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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