Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab23724)

Overview

  • Product nameAnti-Prostaglandin D Synthase (hematopoietic) antibody
    See all Prostaglandin D Synthase (hematopoietic) primary antibodies
  • Description
    Rabbit polyclonal to Prostaglandin D Synthase (hematopoietic)
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Full length native protein (purified) (Rat).

  • General notes


    This antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: Whole serum
  • PurityWhole antiserum
  • Primary antibody notesThis antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab23724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/800. Predicted molecular weight: 22 kDa.
ELISA 1/800.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionBifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • Tissue specificityExpressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • Sequence similaritiesBelongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • Developmental stageHighest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cerebrin 28 antibody
    • Glutathione dependent PGD synthetase antibody
    • Glutathione S-transferase antibody
    • Glutathione-dependent PGD synthase antibody
    • Glutathione-requiring prostaglandin D synthase antibody
    • GST class-sigma antibody
    • H PGDS antibody
    • H-PGDS antibody
    • Haematopoietic prostaglandin D synthase antibody
    • Haematopoietic prostaglandin D2 synthase antibody
    • Hematopoietic prostaglandin D synthase antibody
    • Hpgds antibody
    • HPGDS_HUMAN antibody
    • Prostaglandin D synthase antibody
    • Prostaglandin D2 synthase hematopoietic antibody
    • Prostaglandin H2 D isomerase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS2 antibody
    see all

References for Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab23724)

ab23724 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Rat Tissue lysate - other (Prefrontal Cortex)
Gel Running Conditions Reduced Denaturing
Loading amount 15 µg
Specification Prefrontal Cortex
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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Submitted Nov 19 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"